Micropatterned Silk-Fibroin/Eumelanin Composite Films for Bioelectronic Applications

There has been growing interest in the use of natural bionanomaterials and nanostructured systems for diverse biomedical applications. Such materials can confer unique functional properties as well address concerns pertaining to sustainability production. In this work, we propose biofabrication micropatterned silk fibroin/eumelanin composite thin films be used electroactive bioactive applications bioelectronics engineering. Eumelanin is most common form melanin, naturally derived from ink cuttlefish, having antioxidant properties. Another biomaterial, protein fibroin, modified with photoreactive chemical groups, which allows formation eumelanin different microstructures. The composites are fabricated obtain microstructures using UV curing. Here, report first time preparation, characterization, physical, electrochemical, biological these films. Higher concentrations incorporated into exhibit a higher charge storage capacity good electroactivity even after 100 redox cycles. addition, microscale structure cellular activity assessed understanding composite. developed applied substrates bioapplications (e.g., bioelectronics, sensing, theranostics) because their biocompatible